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New Study: PSA levels in younger men might predict future risk of prostate cancer

mountain-bikers-in-brazil-1-1433086Prostate cancer screening with prostate-specific antigen (PSA) has been shown to reduce death and the spread of prostate cancer to other parts of the body, but the PSA test remains highly controversial as it frequently leads to over diagnosis and over treatment of men who may not be at risk.

Smarter screening strategies that can improve the accuracy of diagnosing lethal prostate cancer are urgently needed. Through a prospective study of US men, investigators from Brigham and Women’s Hospital and the Harvard T.H. Chan School of Public Health have found that measuring PSA levels in younger men (between the ages of 40 and 59) could accurately predict future risk of lethal prostate cancer later in life. Their findings suggest that screening PSA levels in men at mid-life may help identify those who are at greater risk and should be monitored more closely.

“We found a single baseline PSA-level measurement during midlife could accurately predict future risk of lethal prostate cancer,” said co-lead author Mark Preston, MD, MPH, a physician in BWH’s Division of Urology. “These data identify subgroups of men, based on their PSA levels at a given age, who could benefit from screening intervals tailored to their actual magnitude of risk.”

Read the full story here …

Dr. Michael Lazar, a Santa Rosa urologist and prostate cancer expert, is the only Northern California physician recognized as a leader in the use of high-intensity focused ultrasound (HIFU) for prostate cancer. He has been successfully treating patients with HIFU since 2007. Dr. Lazar now offers a HIFU Program in partnership with HIFU Prostate Services, LLC (HPS). HIFU Prostate Services, LLC (HPS) is a leading provider of minimally-invasive prostate cancer treatments using High Intensity Focused Ultrasound (HIFU). HIFU prostate treatments are performed at San Francisco Surgery Center (SFSC). SFSC offers patients a state-of-the-art facility that is convenient to hotels and the airport. For more answers on HIFU visit this page ...  For more information about HIFU treatment or to make an appointment call: (707) 546-5553.

By | June 21st, 2016|News, Prostate Cancer, Urology|0 Comments

California HIFU and Dr. Michael Lazar Recognizes Men’s Health Month With a Look at Prostate Cancer

California HIFU and Dr. Michael Lazar are helping to recognize Men’s Health Month by providing some valuable information and resources for men on Prostate Cancer. The idea behind Men’s Health Month is to heighten the awareness of preventable health problems like prostate cancer, and to encourage early detection and treatment. Dr. Lazar and his staff are proud to be early leaders in the usage of HIFU, a medical procedure that applies high-intensity focused ultrasound energy to locally heat and destroy diseased or damaged tissue with prostate cancer through ablation.

Informed Decision Making

your-questions-answeredAccording to The Center for Disease Control and Prevention (CDC) it is important for men to be aware of prostate cancer risks and to make informed decisions. This happens best when a man—

  • Understands the nature and risk of prostate cancer.
  • Understands the risks of, benefits of, and alternatives to screening.
  • Participates in the decision to be screened or not at a level he desires.
  • Makes a decision consistent with his preferences and values.

The CDC as well as other federal agencies follow the prostate cancer screening recommendations set forth by the U.S. Preventive Services Task Force, which recommends against prostate specific antigen (PSA)-based screening for men who do not have symptoms. Other organizations, like the American Urological Association,[PDF-310KB] the American Cancer Society, and the American College of Physicians may have other recommendations. It is important to talk to a doctor and get routine screenings.

Some men may be having prostate problems and want to learn more about prostate cancer symptoms and risk factors, the PSA screening test, and conditions that are not cancer such as an enlarged prostate (BPH) and prostatitis. To learn more follow this link for practical lists, tips, and medical images …

Knowing your prostate cancer therapy options empowers you to make smart choices

Prostate cancer is the leading solid organ cancer in the USA and the second most common cause of cancer related death. Worldwide, it is the fourth most common cancer with differing biologic activity in different cultures, probably related to different lifestyles. Many prostate cancers can be managed conservatively, especially in elderly men. But larger tumors, those with higher Gleason score and higher (and rising) PSA levels, especially in younger men, should be treated more aggressively.

Prostate Cancer Therapy Options

There are many options available to residents of Northern California. Prostate cancer is usually managed with active surveillance, radiation therapy, surgery to remove the cancerous gland, freezing (cryotherapy), or high intensity focused ultrasound (HIFU). Hormonal therapy is used to control cancer that has spread beyond the prostate and is no longer curable, or for very elderly patients with a limited life expectancy.

High Intensity Focused Ultrasound (HIFU)

HIFU is a FDA approved precise and targeted therapy that reduces the risk of complications caused by surgery and radiation.

HIFU uses ultrasound energy, or sound waves, to heat and destroy specifically targeted areas of tissue. During HIFU, the sound waves pass through healthy tissue without causing damage. However, at the focal point of the sound waves (like a magnifying glass focusing the rays of the sun to burn a leaf), the tissue temperature is raised to 90 degrees Celsius, destroying the targeted tissue.

Learn more about HIFU treatment for prostate cancer …

By | June 14th, 2016|News, Prostate Cancer|0 Comments

Focal Therapy For Prostate Cancer

hifu mini article cropped-logo-square.jpgFocal therapy, often referred to as a “male lumpectomy,” is a general term for a variety of noninvasive techniques for destroying small tumors inside the prostate while leaving the gland intact and sparing most of its normal tissue

As technology has advanced, physicians now have the ability to diagnose patients with prostate cancer earlier which means that often times tumors within the prostate are small and contained to the prostate.

Advanced imaging techniques, allow doctors to pinpoint exactly where the tumor within the prostate is located using multi-parametric MRI and UroNav fusion biopsies, enabling them to target only the tumor within the prostate, leaving other tissue unharmed.

Focal therapy is being studied all over the world because of the large potential for reducing side effects such as urinary incontinence and erectile dysfunction. Additionally, due to the noninvasive nature of focal therapy, treatment and recovery times are dramatically reduced.

Read this article on HIFU Prostate Services.

For more information about HIFU treatment which is now available in San Francisco, or to make an appointment call: (707) 546-5553. Visit us online to learn more at: www.californiahifu.com.

Santa Rosa Urologist Dr. Michael Lazar is Making History with a Nonsurgical, Outpatient Treatment for Prostate Cancer

Dr. Lazar and his staff are proud to be early leaders in the usage of HIFU.

Dr. Lazar and his staff are proud to be early leaders in the usage of HIFU.

High-intensity focused ultrasound (HIFU) waves target cancer cells with precision in a one-to-four-hour procedure that has little or no side affects and a quick recovery rate, giving those diagnosed with prostate cancer another choice over surgery or radiation.

HIFU has been used in other countries for years, and Dr. Lazar has been instrumental in bringing this innovative treatment to the United States. It was approved by the Food and Drug Administration last October, and he has since been performing the procedure at San Francisco Surgery Center for patients who travel from across the country to receive this leading edge treatment.

“The oncological results for HIFU are broadly comparable to radical surgery or radiation but the side effects are less,” says Dr. Lazar. “If the HIFU procedure is performed in the morning, a patient is typically up and around by dinnertime and can often return to normal activity within a few days without the use of pain-killers.”

Dr. Lazar has recently become involved with HIFU Prostate Services, LLC as their Medical Director.  HIFU Prostate Services is the first company to establish centers in the United States offering Sonablate HIFU technology. HIFU Prostate Services makes the non-invasive treatment option available through partnerships with some of the largest urology practices and experienced physicians that establish Sonablate HIFU Centers of Excellence.  Urologists are able to create their own HIFU program and offer treatment within their region. These centers also offer training and proctorship opportunities.

Along with serving as the Medical Director of HIFU Prostate Services, LLC. Dr. Lazar is also a clinical partner with his HIFU Center of Excellence at the state-of-the-art SFSC in downtown San Francisco. Dr. Lazar and his staff are proud to be early leaders in the usage of HIFU. He has worked tirelessly with SonaCare, the manufacturer of the instruments, to bring this innovative service for prostate cancer treatment to patients in the United States.

The HIFU technique is also being developed to treat many other types of cancer including breast, uterine, liver, kidney, and brain.

For those with prostate cancer, HIFU treatment is most effective for patients with early stage cancer, where it is localized to the prostate. It is performed on an out-patient basis that takes one to four hours. A urinary catheter is placed after the procedure for one to three weeks.

While some patients might experience slight irritation, “some patients can have a catheter and they don’t even know it.”

The procedure preserves healthy tissue and nerves, so urine flow and erectile function is maintained in a high percent of cases, as compared to radical surgery or radiation.

Another advantage is recovery time. With surgery or radiation treatment, recuperation time for patients is six to eight weeks, whereas HIFU patients return to normal activities within days.

Dr-michael-lazarDr. Lazar has been treating U.S. prostate cancer patients in Mexico since 2007, where he performed hundreds of outpatient procedures at a U.S. Joint Commission approved bilingual hospital. There, he also served as a HIFU instructor for other physicians and is now training doctors in San Francisco.

Because the treatment is so new, it will take another couple of years before it will be routinely covered by insurance. Those with non-Medicare insurance may get reimbursed to varying degrees.

“What will really make this explode is when the insurance companies are routinely covering the procedure and it will become widely available to all patients. The costs for this procedure are drastically less than for radical surgical and radiation procedures, and with fewer complications so insurance companies will be incentivized to cover it,” Dr. Lazar commented.

As soon as more doctors are trained to perform the procedure in San Francisco, Dr. Lazar plans to bring the treatment to his Santa Rosa office.

“I expect as word gets out there will be a progressive demand for this procedure, so training physicians will be a high priority. It’s already expanding rapidly and we put in an order for our tenth machine,” said Dr. Lazar, adding he won’t be giving up his general urology practice any time soon. “This is what I love to do.”

 

 

 

New Study Reveals Prostate Cancer Metastasis Risk Higher in Some AS Patients

Metastases develop in a small proportion of patients placed on active surveillance (AS) for prostate cancer (PCa), but the risk is significantly higher in some men than others, such as those with Gleason 7 tumors, a new study found.

In a study of 980 men placed on AS—769 with low-risk and 211 with intermediate-risk PCa—a team led by Laurence Klotz, MD, of Sunnybrook Health Sciences Centre in Toronto found that 30 men (3%) progressed to metastatic disease at a median of 6.3 year after diagnosis, according to study findings published in The Journal of Urology (2016;195:1409-1414). Metastases developed in 13 (10%) of 133 patients with Gleason 7 disease.

Metastases occurred in 16 low-risk and 14 intermediate-risk patients, and developed in bone in 18 patients and lymph nodes in 13. Of the 30 men, 15 died from PCa, 4 died of other causes, and 11 are alive with metastases.

Patients with intermediate-risk disease were at higher risk for metastasis, but those with Gleason score 6 and PSA level greater than 10 ng/mL were not at increased risk.

In multivariate analysis, a PSA doubling time less than 3 years versus greater than 3 years was associated with a 3.7-fold increased risk of metastasis. Gleason score 7 compared with 6 was associated with a 3-fold increased risk. The presence of 3 or more positive biopsy cores was associated with a 2.7-fold increased risk compared with fewer positive cores.

The authors concluded that AS appears safe in patients at low risk and in select patients at intermediate risk, particularly those with Gleason score 6 and PSA levels greater than 10 ng/mL. The presence of Gleason pattern 4 on diagnostic biopsy was associated with a 3-fold to 4-fold increased risk of metastasis. Patients with Gleason pattern 4 should be offered active surveillance with caution, according to the investigators.

In editorial comments accompanying the new report, Michael O. Koch, MD, of the Indiana University School of Medicine in Indianapolis, said Dr. Klotz and his colleagues contribute to the growing body of knowledge of the usefulness of AS for managing PCa, but observed: “While the authors have highlighted the risk factors for developing metastases in patients treated with AS, they may be overly optimistic about the safety of this management strategy, particularly in patients with Gleason 7 disease.”

Dr. Koch pointed out that the median follow-up was only 6.3 years, so the number of patients with Gleason 7 disease in whom metastases will develop will grow even more. “As of now AS would appear to be ill-advised in this group of patients,” he noted.

Source: http://www.renalandurologynews.com

For more information about HIFU treatment which is now available in San Francisco, or to make an appointment call: (707) 546-5553. Visit us online to learn more at: www.californiahifu.com

See this article on Renal & Urology News …

By | April 13th, 2016|HIFU, News, Urology|0 Comments

HIFU San Francisco – Meet Dr. Michael Lazar

HIFU 4.12 pic 1.2Michael J. Lazar, MD was an early user of the HIFU technology dating back to 2007.  He was credentialed as proctor in 2010 and participated in editing the user manual for the Sonablate HIFU system. Lazar trained FDA investigators on HIFU patient care and was commissioned by SonaCare Medical to proctor FDA clinical trial cases.  He has treated or been involved with over 200 patients and is also site director for SonaCare Medical’s international training site in Puerto Vallarta, Mexico.

Dr. Lazar has been certified by the American Board of Urology four times and has practiced in Santa Rosa, Calif. since 1983.  He is chairman of the Board of Redwood Health Services, Inc. providing insurance products for employee groups. Dr. Lazar is also CEO and managing director of Santa Rosa Surgical Management Company, LLC that manages the ambulatory surgery center at Santa Rosa Memorial Hospital.  He has participated in medical staff leadership and has served as hospital chief-of-staff and well as departmental and section chairs.  Dr. Lazar received his urology training at Louisiana State University in New Orleans, La. and is a graduate of University of Arkansas Medical School.

California HIFU

Dr. Lazar formed California HIFU in order to offer minimally invasive prostate cancer treatment to men with the Sonablate. He performs HIFU at HIFU Center of Excellence In San Francisco, 450 Sutter Street, Suite 500, San Francisco, CA 94108

HIFU Center of Excellence offers patients a state-of-the-art facility in downtown that is convenient to hotels and the airport for patients interested in traveling from around the country for this recently FDA-cleared treatment. For more information about HIFU treatment which is now available in San Francisco, or to make an appointment call: (707) 546-5553. Visit us online to learn more at: www.californiahifu.com

See more on the HIFU Prostate Services website.

By | April 12th, 2016|Dr. Michael Lazar, HIFU, News|0 Comments

HIFU Center of Excellence in San Francisco

HIFU 4.12 pic 1Sonablate HIFU is available now with Dr. Michael Lazar at HIFU Center of Excellence In San Francisco located in downtown San Francisco, 450 Sutter Street, Suite 500, San Francisco, CA 94108

HIFU Center of Excellence offers patients a state-of-the-art facility in downtown that is convenient to hotels and the airport for patients interested in traveling from around the country for this recently FDA-cleared treatment. For more information about HIFU treatment which is now available in San Francisco, or to make an appointment call: (707) 546-5553. Visit us online to learn more at: www.californiahifu.com

HIFU 4.12 pic 1.2Physician Practicing HIFU in San Francisco: Dr. Michael Lazar

See more on the HIFU Prostate Services Website.

By | April 12th, 2016|Dr. Michael Lazar, HIFU, News|0 Comments

Prostate cancer treatment which avoids harming sexual performance soon available on NHS

A revolutionary prostate cancer treatment which avoids harming men’s sexual performance could soon be available on the NHS.

High Intensity Focused Ultrasound kills the tumour with heat without damaging healthy tissue around it.

In an NHS trial led by University College Hospital, London, 625 men were treated. After five years 93% were cancer-free.

Only 15% had erectile problems compared with 30 to 60% following surgery.

The results were revealed to the European Association of Urology in Munich.

 

Read the full story …

By | April 5th, 2016|HIFU, News, Prostate Cancer, Testimonials|0 Comments

HIFU Prostate Services Expands Management Team with Chief Operating Officer

John McLean brings significant amount of experience in HIFU, operations, marketing and medical imaging.

CHARLOTTE, N.C. March 9, 2016. HIFU Prostate Services, LLC, a leading provider of minimally invasive prostate cancer treatments using high intensity focused ultrasound (“HIFU”), is pleased to announce the addition of John McLean as chief operating officer. McLean brings 17 years of experience in healthcare marketing and management to HIFU Prostate Services and will be responsible for managing treatment teams, training programs and marketing initiatives.

Prior to joining HIFU Prostate Services, McLean spent eight years at SonaCare Medical where he was involved in approximately 600 HIFU cases. While at SonaCare Medical, McLean served as product manager, business manager and service engineer; he brings experience in all areas of running a successful HIFU business.

“After working with John McLean at SonaCare Medical for eight years, it was clear that HIFU Prostate Services could benefit significantly from his experience as we continue to partner with leading urologists and place HIFU systems in the U.S. market.  He will be instrumental in our continued growth and expansion,” said John W. Linn, chief executive officer of HIFU Prostate Services.

“After leaving SonaCare Medical in January, I knew I wanted to continue to work with HIFU technology and help make it more accessible for patients looking for a minimally invasive treatment option. I interviewed several different HIFU companies that are offering treatment as I searched for the one that excelled most in quality of patient care, physician development and advancement of the HIFU technology. It was clear that HIFU Prostate Services has the superior national platform with an experienced HIFU staff and physician network focused on excellent patient care and physician training,” said McLean.

Previously, McLean spent more than nine years in various leadership roles in healthcare ranging from medical imaging companies, healthcare service companies and the U.S. Army; these experiences give him a unique insight into the healthcare industry. McLean has set up and run healthcare support in hospitals, outpatient surgery centers and combat-support hospitals.

HIFU Prostate Services was the first company to offer treatment using Sonablate HIFU technology in November 2015. The company rapidly expanded operations into four centers that will treat nearly 30 patients in March and three additional centers are planned to open this spring.

“We are thrilled to have John on board; his role will focus on the continued growth of the company’s existing treatment centers and support expansion as the company adds six additional treatment locations in the coming months,” said John Harris, chairman of HIFU Prostate Services.

About HIFU Prostate Services, LLC

HIFU Prostate Services (HPS) is the nation’s leading provider of minimally invasive prostate cancer treatment using high intensity focused ultrasound. HPS was founded to provide men access to a less invasive treatment option for prostate cancer that has the ability to eliminate cancer and preserve patient quality of life. Our mission is to deliver the highest quality of care, support, and technology to the patient and to the urology community for the treatment of localized prostate cancer using high intensity focused ultrasound (HIFU) with the Sonablate. HPS was founded in 2015 by a seasoned management team with over 50 years of experience in the healthcare industry and over 30 years focused on HIFU technologies.

HPS has the most experienced HIFU staff in the country with over 60 years of combined HIFU experience. HPS nurses and technicians have been involved in over 3,000 HIFU procedures. The HPS network includes 100 physicians across the U.S., and our physician proctors have experience with over 1,200 HIFU procedures. The company is headquartered in Charlotte, NC and has established partnerships with physicians and urology practices throughout the country.

For more information about HIFU or to make an appointment call (707) 546-5553. Find us online at: www.californiahifu.com.

 

By | March 29th, 2016|Dr. Michael Lazar, HIFU, News|0 Comments

Prostate cancer targeted with ultrasound ‘could transform treatment’

man-at-lake-1374960The study – on the effectiveness of high-intensity focused ultrasound (HIFU) to treat men with localized prostate cancer – featured at the European Association of Urology Congress (EAU16) in Munich, Germany, March 11-15, 2016.

Led by University College Hospital (UCH) in London, UK, the study followed 625 men between 2004-2015, who were treated in the UK and who had localized, non-metastatic tumors; the tumors were in one part of the prostate and had not spread beyond the gland.

Hashim Ahmed, a consultant urological surgeon at UCH, told the meeting that 93% of patients who underwent HIFU alone to remove their prostate tumor were still cancer-free and did not need any surgery or radiotherapy 5 years after treatment. The results follow those of an earlier study by Ahmed and colleagues published in The Lancet Oncology in 2012, where, of 41 men who underwent HIFU, 95% were free of cancer after 12 months. Not one of the patients developed incontinence, and only 1 in 10 suffered erectile dysfunction.

In the new, larger study, which reports medium-term results, only 1-2% of the HIFU patients experienced long-term incontinence, and just 15% suffered erectile dysfunction. These figures compare favorably with men who have surgery, where around 30-60% experience these distressing side effects. Read the full story …

By | March 29th, 2016|Dr. Michael Lazar, HIFU, News, Prostate Cancer|0 Comments