Random PSA screening misses some aggressive and lethal prostate cancers

UK researchers say that inviting men with no symptoms to a one-off PSA test for prostate cancer does not save lives. This from the largest ever prostate cancer trial conducted over 10 years by Cancer Research UK-funded scientists and published in the Journal of the American Medical Association (JAMA). Researchers at the Universities of Bristol and Oxford found that testing asymptomatic men with PSA detects some disease that would be unlikely to cause any harm but also misses some aggressive and lethal prostate cancers. This highlights the flaws of a single PSA test as a way to screen for prostate cancer, and shows the need to find more accurate ways to diagnose cancers that need to be treated. The CAP Trial, which spanned almost [...]

2018-03-13T10:59:50+00:00 March 13th, 2018|

New PET scan targets copper in tumors to detect prostate cancer

An Italian study featured in the March issue of The Journal of Nuclear Medicine demonstrates that a novel nuclear medicine imaging agent targeting copper accumulation in tumors can detect prostate cancer recurrence early in patients with biochemical relapse (rising prostate-specific antigen [PSA] level). Copper tends to be more concentrated in tumors, making it a good imaging biomarker. For this study of 50 patients, researchers conducted PET/CT scans comparing the new imaging agent, copper-64 chloride (64CuCl2), with fluorine-18-choline (18F-Choline). Multiparametric magnetic resonance imaging (mpMRI) was also conducted. In addition to calculating the detection rate of each imaging modality, the biodistribution, kinetics of the lesions and radiation dosimetry of 64CuCl2 were evaluated. "This is the first time this novel agent has been compared with 18F-Choline-PET/CT in a considerable number of prostate [...]

2018-03-06T07:35:43+00:00 March 6th, 2018|

New study shows that some cases of aggressive prostate cancer may be linked to high-fat diet

Dr. Michael Lazar of California HIFU shares insights from a new study on prostate cancer, emphasizing that a healthy diet may contribute to prevention of the disease. There have been many discoveries recently that identify a link between a diet rich in fatty foods and increased risk of prostate cancer. The evidence continues to mount with the results of this new study investigating the effects of high-fat diets on certain prostate cancer tumors. Researchers at the Cancer Center at Beth Israel Deaconess Medical Center (BIDMC) discovered genetic mechanisms that promote cancer tumor metastasis, pointing to the typical Western high-fat diet as a key factor in driving that metastasis. The study was published this week in two journals; Nature Genetic and Nature Communications. It compared [...]

2018-01-23T09:50:13+00:00 January 23rd, 2018|

#1 New Year’s Resolution for Men: Get screened for prostate cancer

#1 New Year’s Resolution for Men: Get screened for prostate cancer   Santa Rosa urologist and prostate cancer expert Dr. Michael Lazar provides an overview of prostate cancer screening options; says early detection saves lives. “Knowing the many options for treating prostate cancer is something all men at risk of developing the disease need to be informed about,” says Dr. Lazar. “Most men know about the unpleasant side effects that go along with traditional models of prostate cancer treatment, including urinary incontinence, bowel and erectile dysfunction. But some of the newer treatment modalities such as HIFU (high-intensity focused ultrasound) can only be undertaken at the early stages, when damage to surrounding tissue can best be mitigated, and most side effects eliminated.” Why Early [...]

2018-01-02T13:01:35+00:00 January 2nd, 2018|

Research News: Reduced Risk of Prostate Cancer in Men with Low Testosterone

Men with unusually low amounts of testosterone in their blood are around 20% less likely to develop prostate cancer, according to new research presented at the National Cancer Research Institute (NCRI) Cancer Conference in Liverpool. Scientists from the University of Oxford conducted the largest analysis of hormones and prostate cancer risk to date. The study – funded by Cancer Research UK – looked at blood samples from around 19,000 men aged 34-76 years, collected between 1959 and 2004. Of these men 6,900 went on to develop prostate cancer. The researchers divided the 19,000 men into ten groups – ranging from men with the lowest amount of testosterone in their blood to those with the highest, and compared their prostate cancer risk. They found that men [...]

2017-12-13T13:37:18+00:00 November 8th, 2017|

California HIFU Shares Prostate Cancer Facts for National Prostate Cancer Month

September is National Prostate Cancer Awareness Month. Prostate cancer is the most common type of cancer among men in the US, other than skin cancer.  What are the symptoms of prostate cancer? Early prostate cancer usually causes no symptoms. Men who have prostate cancer can be symptom-free for years. But as it grows, prostate cancer can cause some symptoms. Men should see a health care provider if they: Have to urinate often, especially at night Have trouble starting or stopping urine flow Have a weak or slow urine flow Have blood in the urine or semen Feel frequent pain or stiffness in the lower back, hips, or ribs Conditions other than prostate cancer could cause these symptoms. But the only way to know what’s causing them is [...]

2017-12-13T13:37:19+00:00 September 12th, 2017|

How to Know When HIFU is the Right Treatment Option for Prostate Cancer

Is HIFU Prostate Cancer Treatment for You? HIFU is an FDA approved precise and targeted therapy that reduces the risk of complications caused by surgery and radiation. HIFU uses ultrasound energy, or sound waves, to heat and destroy specifically targeted areas of tissue. During HIFU, the sound waves pass through healthy tissue without causing damage. At the focal point of the sound waves (like a magnifying glass focusing the rays of the sun to burn a leaf), the tissue temperature is raised to 90 degrees Celsius, destroying the targeted tissue. When HIFU is the best option HIFU uses ultrasound energy, or sound waves, to heat and destroy specifically targeted areas of tissue. During HIFU, the sound waves pass through healthy tissue without causing damage. However, at the [...]

2017-12-13T13:37:19+00:00 August 15th, 2017|

Cyclist is back doing what he likes best after HIFU procedure

Matthew Hoffman, 59, was having regular annual physical exams that included blood tests. In 2010 one test showed that the Prostate-­Specific Antigen (PSA) was high. Dr. Michael Lazar advised him to have a biopsy, which was negative. However, precursors for cancer were present, meaning that his situation had to be watched closely. A year later, his PSA level had risen to 7. Another biopsy confirmed that something should to be done. “Dr. Lazar explained various options, including surgery, radiation and High Intensity Focused Ultrasound (HIFU). Most of the alternatives had side effects I didn’t like, so I chose HIFU. Overall, it was a pretty good experience.” As an engineer involved with developing software to test cell phones, Matthew was intrigued by the fact that high intensity sound waves could be used as medical therapy. As this happened before HIFU became FDA approved, [...]

2017-12-13T13:37:19+00:00 August 8th, 2017|

After 20 years of scrutiny researchers confirm surgery for early prostate cancer may not save lives

Dr. Michael Lazar Director of California HIFU discusses HIFU for Prostate Cancer and the findings of latest study which reveals that radical surgery is not the best way to treat early stage prostate cancer. New treatment options are available and patients need to know.  A 20-year-long study by a national research team including Washington University School of Medicine in St. Louis, and led by the Minneapolis Veterans Administration Health Care System overwhelmingly supports growing evidence that prostate cancer surgery performed on men in the early stages of the disease offers very few if any benefits. In the cases involved with this study, surgery did not prolong life and often caused serious complications including; infection, urinary incontinence and erectile dysfunction. “As treatments for prostate cancer continue [...]

2017-12-13T13:37:19+00:00 July 25th, 2017|