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Tuesday 30 Sep 2008

From Duke University as presented at the American Urology Association meeting this year, and reported in Renal and Urology News:

Dr. Lionel L Banez’ group found that for every 1 mg/dl rise in total cholesterol or LDL cholesterol, the risk for recurrence after radical prostatectomy rose 1%. Men with total cholesterol levels of >217 had a 2.5 times higher risk for biochemical recurrence (PSA) than men with cholesterol <167. Statins may be investigated as possible agents in the treatment of prostate cancer.

Seeking the “Trifecta”

The Memorial Sloan Kettering (MSK) Cancer Medical Center is one of the top 3 cancer hospitals in the country. A review of their radical prostatectomy results sought to determine how often they achieved the optimal results of: 1. cancer cure (per PSA)
2. full continence
3. no erectile dysfunction (need Viagra or equivalent only)

This “Trifecta” happened at: 1 year—30%
2 years–42%
3 years–47%
4 years–53%

These are the numbers for T1C and T2A cancers.

Aranchuk, et al., J Clin Onc, 23:18, 4146-51.

Be careful when getting overly optimistic quotes from local surgeons regarding their results.

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